Effect of Different Laser on Rats with Hypolekocytosis

摘要：

Objective: To assess the effect of 10.6 μm laser and 650 nm laser simultaneous or separate irradiation on rats with hypolekocytosis.Methods: 60 Wistar Rats,50％ male and 50％ female with normal white cell count (WBC) in blood and weight 180-220g,were randomly allocated to control,model,sham laser,10.6μm laser,650 nm laser and 10.6 μm+650 nm laser group,10 in each group.The hypolekocytosis model was established by I.p.cyclophosphamide 100g/kg weight.Corresponding laser irradiation was administration on Zusanli (ST 36) and Dazhui (GV 14) for 1 min,once per day,8 times totally.The WBC in blood collected from tail end every two days after the model was established was taken as assess index.Results: The WBC of rats decreased continuely from the second day after injected cyclophosphamide,and to the lowest level on the fifth day,then began to recover.The WBC of 10.6 μm +650 nm laser group reached the normal level after 8 times laser irradiation,and had no difference with the control group (P>0.01),but the model,sham laser,10.6 μm laser and 650 nm laser group had very significant difference with the control group (P<0.001).Conclusion: 10.6 μm CO2 laser and 650 nm semiconductor laser simultaneously irradiating Zusanli(ST 36)and Dazhui(GV 14) can accelerate the recovery of the WBC in the rat with hypolekocytosis.But neither 10.6 μm CO2 laser nor 650 nm semiconductor laser irradiation can does it.Therefore it is suggested that a synergetic effect can be induced when the both lasers irradiate simultaneously.

作者: DENG Hai-ping SHEN Xue-yong ZHAO Ling HUANG Zou-qin WANG Min SHANG Yan-yan

作者单位: Shanghai University of Traditional Chinese Medicine,Shanghai 201203,P.R.China

会议类型: 国际会议

会议名称: The 3rd Workshop on Scientific Approaches to Chinese Medicine(第三届中医科学研究方法研讨会)

会议地点: 安徽黄山

会议语种:英文

页码: 300

在线出版日期: 2008-10-25（万方平台首次上网日期，不代表论文的发表时间）