SELECTIVE SYNTHESIS OF BIODEGRADABLE MATERIALS AND HIGH PERFORMANCE RUBBERS
Polylactides (PLAs) are the most promising biodegradable and biocompatible synthetic macromolecules, possessing versatile physical properties and having been widely used in medicine,pharmaceutics and tissue engineering such as medium for control-release of drug, scaffold, and delivery of antibody and gene. The applications are strongly dependent on the microstructures of PLAs.Ring-opening polymerization (ROP) of iactide (LA) by single-site catalysts is the most efficient manner to obtain PLAs with predicted molecular weight and narrow molecular weight distribution, and significantly, tacticity. The past two decades have witnessed the development of catalysts for such aims.Most of catalysts have been explored to initiate the ROP of optically pure D-LA or L-LA to yield isotactie PLA with the retention of configuration, however, for the racemic lactide (rac-LA), atactic PLA is usually isolated. Stereoselective polymerization of rac-LA is initially accessed by employing optically pure Salen aluminum initiator and homochiral and racemic Salen aluminum initiators or achiral Salen aluminum alkoxides. Contrarily, studies on synthesis of heterotactic PLA have remained less explored.
Xinli Liu Shihuili Baoli Wang Wei Gao Dongmei Cui
State Key Laboratory of Polymer Physics and Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China
国际会议
5th International Symposium on High-Tech Polymer Materials(HTPM-V)(第五届国际高技术高分子材料学术会议)
北京
英文
21-22
2008-10-27（万方平台首次上网日期，不代表论文的发表时间）