SUPRAMOLECULAR POLYMERIC BIOMATERIALS FOR DRUG AND GENE DELIVERY
The phenomena of molecular self-assembly have inspired interesting development of novel functional materials for electronic and biomedical applications. We have been focusing on developing novel macromolecules with the ability to self-assemble into more elaborate supramolecular structures, which can function as biomaterials for potential drug/gene delivery and tissue engineering applications. The key components in our macromolecular self-assembling structures include the biodegradable and biocompatible microbial biopolyesters, poly(β-hydroxyalkanoates),and the macrocyclic polysaccharides, cyclodextrins. A series of novel block copolymers and interlocked supramolecular architectures were designed and synthesized. They were characterized in terms of their molecular and supramolecular structures, as well as their properties and functions as biomaterials for potential drug delivery, gene delivery, and tissue engineering.
Jun Li
Division of Bioengineering,Faculty of Engineering,National University of Singapore,7 Engineering Drive 1,Singapore 117564;Institute of Materials Research and Engineering,A*STAR (Agency for Science,Technology and Research),3 Research Link,Singapore 117602
国际会议
5th International Symposium on High-Tech Polymer Materials(HTPM-V)(第五届国际高技术高分子材料学术会议)
北京
英文
15
2008-10-27（万方平台首次上网日期，不代表论文的发表时间）