Towards Automated Nanomanipulation of Nano-Bio-Entities using Real-Time Molecular Force Feedback Information

摘要：

Bovine insulin molecular aggregates, a nano-scale bio-entity, has been manipulated using P-NUVO (Programmable nanomanipulation using vibration-mode operation AFM) method. This method uses the amplitude of an AFM cantilevers vibration as real-time feedback information to detect the boundary of the nano-entities under manipulation. This amplitude signal changes as a function of the distance between the probe-tip and a nano-entity due to their inter-molecular force interactions. The AFM tips manipulating path could also be planned according to the manipulation task. Different configuration of bio-nano-entities, i.e., sphere and rod configurations were manipulated. Due to the difficulties of the sample preparation process, the real-time feedback information did not work as well as for other nano-entities such as carbon nanotubes.

关键词： AFM Automated nanomanipulation Bio-nano-manipulation Programmable nanomanipulation Nano-robotics.

作者: Yongliang Yang Zaili Dong Wen J. Li

作者单位: State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, She State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, She State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, She

会议类型: 国际会议

会议名称: 2008 IEEE International Conference on Onformation and Automation(IEEE 信息与自动化国际会议)

会议地点: 张家界

会议语种:英文

页码: 1490-1493

在线出版日期: 2008-06-20（万方平台首次上网日期，不代表论文的发表时间）