Design and Preparation of a Surgical Biomaterial Patch
The biomaterial patch of electrospun collagen type I fibers was designed and prepared successfully in this study. Electrospun collagen fibrous patches were produced by electrospinning of 7 various levels of concentrations (ranged from 8% to 20%w/v) of collagen solutions. The tensile strength,yield strength and elastic modulus of 7 groups of electrospun collagen fibrous patches were determined in dry conditions using the electronic tensile test machine. The mechanical properties of 2 groups of above were recommended as a suitable surgical patch for clinical transplantation. The results showed no significant differences versus fresh porcine pericardium as controls. The SEM images of the 2 groups showed that the patches were smooth and uniform with the interwoven and porous morphology. So the electrospun collagen fibrous patches have a great potential as a surgical biomaterial patch.
Electrospun Collagen Surgical patch Biomechanics
Hai Lu Bo Jiang WeiJun Chen Yan Xing Dajun Ying
Department of Anatomy, Key Lab of Biomechanics and Tissue Engineering, Third Military Medical Univer National Institute of Biomaterial Engineering, Sichuan University, Chengdu 610064, China
国际会议
北京
英文
26-30
2008-11-06（万方平台首次上网日期，不代表论文的发表时间）