DNA METHYLATION OF MOUSE OOCYTES DERIVED FROM IN VITRO CULTURED PRIMORDIAL GERM CELL

摘要：

In recent several years, it has become increasingly clear that epigenetic regulation of gene expression is critical during mammalian oogenesis. Many genes categorized as imprinted gene which is regulated by epigenetic modification of DNA methylation in differentially methylated region (DMR) are exclusively expressed either from maternal or paternal allele. Few imprinted genes have been found to acquire a methylation marker in the female germ line. Research on the development of mammalian ovarian oocyte has primarily focused either on early development stage of germ cells or on later postnatal follicular growth and maturation.

关键词： DNA methylation DMR imprint gene mouse primordial germ cell oocyte

作者: Zhenhua Song Zhanbiao Li Pan Zhang Jianxing Chen Qingjie Pan Wei Shen

作者单位: Institute of Animal Reproduction Development and Genetic Engineering, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China

会议类型: 国际会议

会议名称: The 5th Annual Conference of the Asian Reproductive Biotechnology Society(第五届亚洲动物繁殖生物技术大会)

会议地点: 昆明

会议语种:英文

页码: 163

在线出版日期: 2008-11-26（万方平台首次上网日期，不代表论文的发表时间）