GENETIC AND EPIGENETIC CONTROLS DURING EARLY EMBRYO DEVELOPMENT IN MAMMALS

摘要：

IntroductionEpigenetics is defined as heritable changes in gene expression without changes in DNA sequence. Normal development depends on a precise sequence of changes in the configuration of the chromatin, which are primarily related to the acetylation and methylation status of histones and the methylation of genomic DNA. During germ cell development, epigenetic reprogramming of DNA methylation resets parent-of-origin based genomic imprints and restores totipotency to gametes.

作者: Nam-Hyung KIM

作者单位: Department of Animal Sciences, Chungbuk National University

会议类型: 国际会议

会议名称: The 5th Annual Conference of the Asian Reproductive Biotechnology Society(第五届亚洲动物繁殖生物技术大会)

会议地点: 昆明

会议语种:英文

页码: 15-17

在线出版日期: 2008-11-26（万方平台首次上网日期，不代表论文的发表时间）