Functional graded electrospun gelatin-chitosan polyurethane scaffolds for cardiovascular tissue engineering

摘要：

Electrospinning can be used to produce thin scaffolds suitable for applications, such as heart valve leaflets and cardiovascular field. Since the native important for the chosen material to be robust, flexible and possess comparable mechanical properties. Thermoplastic polyurethane is a suitable polymer for such cardiovascular application due to its elasticity, flexibility and good mechanical strength. This study created a trilayered scaffold with polyurethane sandwiched on each side by gelatin-chitosan layer and aimed to investigate its biocompatibility. The nanaofibrous configuration and good biocompatibility of electrospun gelatin-chitosan polyurethane demonstrated its potential as a biomaterial for cardiovascular tissue engineering.

关键词： electrospinning thermoplastic polyurethane gelatin-chitosan cell retention

作者: Chen R Wong CS Patel SS Ke QF Morsi YS Mo XM

作者单位: College of textiles, Donghua University, Shanghai, 200051, China Institute of Biotechnology, Deakin University, Waurn Ponds, Geelong, VIC,3217, Australia Biomechanics and Tissue Engineering Group, IRIS, Swinburne University of Technology, Hawthorn, VIC, College of Biological Sciences and Biotechnology, Donghua University, Shanghai,200051, China

会议类型: 国际会议

会议名称: The 12th Asian Pacific Confederation of Chemical Engineering Congress(第十二届亚太化工联盟大会暨化工展览会)

会议地点: 大连

会议语种:英文

在线出版日期: 2008-08-04（万方平台首次上网日期，不代表论文的发表时间）