Unlocking the Molecular Secrets of Ginseng as a Platform for Drug Discovery

摘要：

Post-genomic Era of Traditional Chinese MedicineDespite high expectations,genomics-based drug discovery to date has been disappointing.The multifactorial nature of chronic diseases is probably the most significant problem in target discovery.Surprisingly,only 600-1,500 genes of the ～30,000 genes in the human genome are thought to be potential drug targets 1.In fact,6,000-plus currently marketed drugs interact with less than 120 molecular targets,and the 100 best-selling drugs interact with 43 targets.A quick survey reveals that 61% of the 877 drugs introduced between 1981-2002 could be traced to,or inspired by,natural products,and 74% of anticancer drugs in current use are derived from nature.

作者: Fan Tai-Ping

作者单位: Angiogenesis & TCM Laboratory,Department of Pharmacology,University of Cambridge Cambridge CB2 1PD,United Kingdom

会议类型: 国际会议

会议名称: 2008 International Conference on Ginseng(2008国际人参会议)

会议地点: 长春

会议语种:英文

页码: 2-7

在线出版日期: 2008-09-01（万方平台首次上网日期，不代表论文的发表时间）