Predicting Non-protein-coding RNA Genes in Escherichia Coli Using SVM with Signature Descriptor
Non-protein-coding RNA (ncRNA) genes are known to play significant roles. Along with transfer RNAs, ribosomal RNAs and mRNAs, ncRNAs contribute to gene splicing, nucleotide modification, protein transport and regulation of gene expression. Several methods exist for predicting ncRNA genes in Escherichia coli (E.coli). In this paper, we describe a very general, highthroughput method for predicting ncRNA genes in E.coli. The method predicts more than two hundred intergenic regions to contain ncRNA genes, and over half of these overlap with previous tested candidates. Our results indicate that the number of ncRNA genes in E.coli is larger than what has previously been estimated.
Escherichia coil non-protein-coding RNA SVM signature descriptor
Hong-Wei Liu
School of Information, Beijing Wuzi University, Beijing 101149, China Institute of Applied Mathematics Academy of Mathematics and Systems Science, CAS, Beijing 100080, China
国际会议
The Second International Symposium(OSB08)(第二届国际优化及系统生物学学术会议)
云南丽江
英文
287-293
2008-10-31（万方平台首次上网日期，不代表论文的发表时间）