Influence of Stimulation Parameters on the De-Synchronization in Vagues Nerve Stimulation Therapy with Epileqsy

摘要：

The influence of the stimulation intensity and frequency on the de-synchronization is numerically investigated in globally coupled neural networks and its possible implications for vagus nerve stimulation therapy with epilepsy. The simulations show that synchronization evolves into de-synchronization in the network when a part (about 10 percent) of neurons are stimulated with a pulse current signal. The network desynchronization appears to be sensitive to the stimulation frequency and intensity. For the case of the same stimulation intensity, those weakly coupled networks reach de-synchronization more easily than strongly coupled networks.

作者: Yanlong Li Wenke Xu Jun Ma Zhaoyang Chen

作者单位: Institute of Theoretical Physics Lanzhou University of Technology Lanzhou, China 730050 Department of Chemistry The George Washington University Washington, USA 20052

会议类型: 国际会议

会议名称: Fourth International Conference on Impulsive and Hybrid Dynamical Systems(ICIHDS 2007)(第四届国际脉冲和混合动力系统学术会议)

会议地点: 南宁

会议语种:英文

在线出版日期: 2007-07-20（万方平台首次上网日期，不代表论文的发表时间）