Novel Sample Introduction and Detection Techniques in Microchip Capillary Electrophoresis
(0) Capillary electrophoresis (CE) and related techniques on microchip have made great extensions in recent years. This study describes some advanced sample introduction and detection techniques in microchip CE. First, a diffusion-free sampling and labeling method has been proposed for sub-cellular analysis based on ionic liquid segmentation where could perform an on-line labeling without time limit. Second, a dual-channel CE in-channel electrochemical detection (ECD) system has been developed to eliminate the effect of separation voltage to EC detector without using a decoupler. The system reduces band broadening, potential shift and improves separation efficiency. Further, a novel fabrication method of nanoband electrode has been developed in dual-channel poly (dimethylsiloxane) (PDMS) microchip for in-channel CE-ECD system. The developed nanoband electrode microchip system shows great separation efficiency and detection sensitivity.
Dual channel IL Segmented sampling Microchip Nanoband electrode
Ming Li Chuanpin Chen Jong Hoon Hahn
Department of Chemistry, BK School of Molecular Science School of Environmental Science and Technology, Pohang University of Science and Technology Pohang, Department of Chemistry, BK School of Molecular Science School of Environmental Science and Technolo
国际会议
The First Shenyang International Colloquium on Micrifluidics(首届沈阳国际微流控学术论坛)
沈阳
英文
19-22
2007-10-21（万方平台首次上网日期，不代表论文的发表时间）