Fabrication of Calcium Alginate Microcapsules Containing Living Cells Using Microfluidic Device

摘要：

A microfluidic device has been used to produce size- controlled polymeric microcapsules containing living cells. The diameter of microcapsules was controlled by changing the flow conditions. The multifunction microfluidic device could produce 20-50μm calcium alginate microcapsules with the coefficients of variation (CV) below 3.7％. Based on this method, we succeeded in encapsulating Saccharomyces cerevisiae and it shows that the calcium alginate microcapsules could be used in immobilized microorganism culture and offered a favorable microenvironment for cell growth.

关键词： Microfluidic device Droplet Cell culture Calcium alginate

作者: Kan Liu Hui-Jiang Ding Jing Liu Yong Chen Xing-Zhong Zhao

作者单位: Department of Physics, Wuhan University, Wuhan, China Center of Nanoscience and Nanotechnology, Wuhan University, Wuhan, China Key Laboratory of Acoustic and Photonic Materials and Devices, Ministry of Education, Wuhan University Wuhan, China

会议类型: 国际会议

会议名称: The First Shenyang International Colloquium on Micrifluidics(首届沈阳国际微流控学术论坛)

会议地点: 沈阳

会议语种:英文

页码: 65-68

在线出版日期: 2007-10-21（万方平台首次上网日期，不代表论文的发表时间）