Direct Measurement of Impaired Erythrocyte Deformability on an Inter-Channel Microfluidic Device
A novel method using inter-channel microfluidic device for erythrocyte deformability measurement is presented here. With good deformability, erythrocyte can be absorbed in the filters which locate between two channels in microfluidic device. At the same time, the leukocyte can not be absorbed for its weaker deformability. Thus, the measurement of erythrocyte deformability can be operated without pretreatment. As a demonstration, different impaired erythrocyte deformability was investigated. Such a microfluidic method has shown its advantages of handling simply, little samples, and without pretreatment of blood. Also, it has the potential application in clinic diagnose.
Microfluidics Erythrocyte Deformability
Xiao-Hai Yang Ling Long Ke-Min Wang Hui-Ming Liu Mei-Lin Li
Biomedical Engineering Center, State Key Laboratory of Chemo/Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, China
国际会议
The First Shenyang International Colloquium on Micrifluidics(首届沈阳国际微流控学术论坛)
沈阳
英文
234-236
2007-10-21（万方平台首次上网日期，不代表论文的发表时间）