Metabonomics and Its Application to Pesticide Toxicology
Metabonomics, which is defined as the quantitative measurement of the dynamic multipara-metric metabolic response of living systems to pathophysiological stimuli or genetic modification,has a wide application perspective in many fields. This approach has been applied for monitoring the environmental pollution of chemical pesticides and the studying of the mechanisms of the pesticide tox-icities. The advantages of application of this approach for pesticide toxicology and the searching of biomarkers of the pesticide poisoning in vivo were reviewed. And the experimental studying for the multiple pesticides toxicities was also described in this article.
metabonomics pesticide toxicity biomarker
Wu Yijun
Laboratory of Molecular Toxicology, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, P. R. China
国际会议
北京
英文
231-236
2007-10-09（万方平台首次上网日期，不代表论文的发表时间）