Design, Synthesis and Fungicidal Activity of SYP-3343
The discovery, synthesis, biological activities, toxicological properties of (E)-methyl 2-(2-((3-(4- chlorophenyl)-1-methyl-1 H-pyrazol-5-yloxy) methyl) phenyl)-3-methoxyacrylate (experimental code SYP- 3343) were introduced in this paper. SYP-3343 was synthesized from 1-(4-chlorophenyl) ethanone as starting material via several steps including cyclization and condensation. The structures of SYP- 3343 and the intermediates were confirmed by NMR, IR, et al. The biological activity test results show that SYP-3343 has good fungicidal activities against downy mildew, rice blast, powdery mildew, anthracnose and so on, and were better than those of the standards. SYP-3343 also showed certain insecticidal and acaricidal activities, which enable it to control plant diseases and pest insects at the same time. Currently SYP-3343 is under development by SYRICI.
(E)-methyl 2-(2-((3-(4-chlorophenyl)-1-methyl-1 H-pyrazol-5-yloxy) methyl) phenyl)-3-methoxyacrylate SYP-3343 synthesis fungicidal activities
Li Miao Liu Changling Li Lin Li Zhengming Li Zhinian Hong Zhang Liang Chen
Agrochemical Discovery Department, Shenyang Research Institute of Chemical Industry, Shenyang 110021 Agrochemical Discovery Department, Shenyang Research Institute of Chemical Industry, Shenyang 110021 Institute of Elemento-organic Chemistry, State Key Laboratory of Elemento-organic Chemistry, Nankai
国际会议
北京
英文
415-421
2007-10-09（万方平台首次上网日期，不代表论文的发表时间）