Synthesis and Biological Activities of N-(4-Substituted-phenyl) -N-(1-β-D-glucopyranosyl)-thiourea

摘要：

Six N-(4-substituted-phenyl)-N-( 2, 3, 4, 6- tetra-O-acetyl-β-D-glucopyranosyl)-thioureas (4) were synthesized by condensation of 4-substituted-anilines (2) with 2, 3, 4, 6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanatc (3) in ethanol under reflux, respectively, and also six N-(4-substituted- phenyl-N-(1-β-D-glucopyranosyl)-thioureas (5) after deacetylation. Their structures were confirmed by IR, <1>HNMR, ESI-MS spectral data and elemental analyses. The biological activities of the compounds were investigated.

关键词： thiourea aniline glucopyranosyl isothiocyanate synthesis biological activity

作者: Wang Baolei Wu Jing Zhu Wenjie Li Yonghong Li Zhengming

作者单位: Research Institute of Elemento-organic Chemistry, State Key Labortary of Elemento-organic Chemistry, Nankai University, Tianjin 300071, P. R. China

会议类型: 国际会议

会议名称: 第三届“农药与环境安全国际学术研讨会暨第七届“植物化学保护和全球法律一体化国际研讨会(3rd International Symposium on Pesticide and Environmental Safety & 7th International Workshop on Crop Protection Chemistry and Regulatory Harmonization)

会议地点: 北京

会议语种:英文

页码: 431-437

在线出版日期: 2007-10-09（万方平台首次上网日期，不代表论文的发表时间）