An Efficient Approach to Synthesis of 2, 5-Disubstituted-1, 3, 4-oxadiazole Containing Furan Using Microwave Irradiation

摘要：

5 novel 2, 5-disubstituted-1, 3, 4-oxadiazoles containing furan Ⅱ a~e have been synthesized respectively by microwave irradiation and conventional heating method in POCI<,3> (phosphorous oxychloride). The reaction time was obviously shortened from 6-8h to 10min, and the yield was increased averagely 13％ under microwave irradiation in comparison to conventional method. The structures of target compounds were identified by IR, MS, <1> HNMR and elemental analysis.

关键词： diacylhydrazine 2, 5-disubstituted-1, 3, 4-oxadiazole microwave irradiation synthesis

作者: Cui Zining Zhou Xinyu Li Ying Huang Juan Wang Zhen Ling Yun Yang Xinling

作者单位: Key Laboratory of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100094, P. R. China

会议类型: 国际会议

会议名称: 第三届“农药与环境安全国际学术研讨会暨第七届“植物化学保护和全球法律一体化国际研讨会(3rd International Symposium on Pesticide and Environmental Safety & 7th International Workshop on Crop Protection Chemistry and Regulatory Harmonization)

会议地点: 北京

会议语种:英文

页码: 438-441

在线出版日期: 2007-10-09（万方平台首次上网日期，不代表论文的发表时间）