Scalp hair as a biomarker in environmental and occupational mercury exposed populations: suitable or not
Hair is a well-established and widely used matrix for measuring mercury exposure of an individual. Although a variety of washing procedures to remove external mercury contamination have been proposed, no standardized procedures are available yet. In this study, different washing reagents like L-cysteine, 2- mercaptoethnol and disodium diaminoethanetetra acetate (EDTA) were used to find out if it is possible to remove mercury contamination from human scalp hair spiked with HgCl2 solutions at different concentrations. It was found that the external mercury contamination could not be fully washed off even using reagents with high affinity to mercury like L-cysteine and 2-mercaptoethanol. However, for the well-pulverized CRM hair powders, some of the endogenous mercury was washed off. It suggests that hair is not a suitable biomarker for evaluation of total mercury exposure especially in people like mercury miners. However, hair still can be used as an indicator for methyl mercury exposure because, generally, there is almost no exogenous contamination of methyl mercury in hair.
biomarker hair ICP-MS mercury
Yu-Feng LI Chunying CHEN Bai LI Jiangxue WANG Yuxi GAO Yuliang ZHAO Zhifang CHAI
Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of
国际会议
第九届痕量元素生物地球化学国际会议(9th International Conference on the Biogeochemistry of Trace Elements)
北京
英文
480-482
2007-07-15（万方平台首次上网日期，不代表论文的发表时间）