Using comet assay of plant nuclei to assess the genotoxicity of cadmium

摘要：

The effects of operation conditions on the comet assay for the detection of DNA damages in plant nuclei were investigated and the application of comet assay in assessing cadmium (Cd) and mixture of Cd and atrazine genotoxicity was studied. The DNA damages in plant nuclei induced by Cd and chemical mixture were detected using comet assay. A dose-dependent increase in DNA damages after Cd treatment was found with increasing Cd concentrations in the growth medium. However the addition of atrazine decrease the genotoxicity of Cd, which may result from the formation of a Cd2 (ATR) compound.

关键词： Comet assay DNA damages Cadmium

作者: A. J. Lin X. H. Zhang Y. G. Zhu

作者单位: Department of Environmental Science and Engineering, Beijing University of Chemical Technology, Beij Beijing City University, Beijing 100083, P. R. China Department of Soil Environmental Science, Research Center for Eco—Environmental SCiences, Chinese Ac

会议类型: 国际会议

会议名称: 第九届痕量元素生物地球化学国际会议(9th International Conference on the Biogeochemistry of Trace Elements)

会议地点: 北京

会议语种:英文

页码: 633-634

在线出版日期: 2007-07-15（万方平台首次上网日期，不代表论文的发表时间）