Study on the characterization of Single-wall carbon Nanotubes covalently functionalized by DNA and the interaction with Riboflavin
Single-wall carbon nanotubes (SWNTs) covalently linked by forming covalent amide bonds between carboxyl groups of the nanotubes and amino groups at the ends of the deoxyribonucleic acid (DNA) oligonucleotides were describes in this paper. FT-IR spectra revealed that DNA was covalently immobilized on the surface of SWNTs. SEM and AFM were employed to characterize the morphology and structure of the DNA-SWNTs. Electrochemical characteristics of DNA-functionalized SWNTs were investigated by cyclic voltammetry. The peak currents for Fe (CN)6 4-/Fe (CN)6 3- redox couple observed in the cyclic voltammograms decreased due to the immobilization of DNA molecules on the surfaces of SWNTs. The results of influence of scan rate suggested that the electrochemical process was controlled by diffusion for DNA-SWNTs electrode. Additionally, the interaction between DNA molecules immobilized on SWNTs and riboflavin (VB2) can be observed obviously by cyclic voltammetry. The present method may provide a way to construct the DNA biosensors based on carbon nanotubes
Single-wall carbon nanotubes DNA functionalized riboflavin electrochemical
张怀 张云怀 肖鹏 李静 李泽全
重庆大学化学化工学院,重庆400030,中国 重庆大学数理学院,重庆400030,中国
国际会议
成都
英文
2007-11-19（万方平台首次上网日期，不代表论文的发表时间）