Preparation of Quantum Dots-tagged Nanospheres by Ultrasonic Emulsification
Hydrophobic CdSe quantum dots (QDs) with high crystallization were synthesized by colloid chemistry method. In this paper, we discussed the influences of reaction time and temperature on granule size and optical property of CdSe QDs. All the samples were characterized by ultraviolet visible spectra (UV-Vis), photoluminescence (PL) and transmission electron microscope (TEM). To improve the fluorescence intensity, the water-solubility, chemical stability and photostability of CdSe core QDs, CdSe/CdS core/shell QDs were prepared using successive ion layer adsorption and reaction (SILAR) method firstly. And then, the CdSe/CdS core/shell quantum dots-tagged nanospheres had been prepared by encapsulating luminescent quantum dots into an amphiphilic polymer using the method of ultrasonic emulsification (O/W). The samples were characterized through photoluminescence (PL) and transmission electron microscope (TEM). The results indicated that QDs-tagged nanospheres were water-soluble, highly stable and bright in fluorescence emission with the size of 70 nm. The modified QDs may have great potential for bio-detection as labeling immunoglobulin.
quantum dots (QDs) amphiphilic polymer bio-detection ultrasonic emulsification fluorescence
成靖 李德娜 张兵波 马贵平 张崎 常津
天津大学材料科学与工程学院纳米生物技术研究所 天津 300072 北京出入境检疫检验局技术中心 北京 100029
国际会议
成都
英文
2007-11-19（万方平台首次上网日期，不代表论文的发表时间）