Preparation and Characteristics of the Composite Magnetic Chitosan Microspheres used as carrier of targeted-drug

摘要：

Firstly, the magnetic Fe3O4 nanoparticles were prepared by chemical co-precipitation with FeCl3·6H2O and FeCl2·4H2O as reactants, NH4OH as precipitation reagent. Composite magnetic chitosan microspheres were prepared with a emulsification crosslinking technique by adding proper amount of glutaraldehyde into chitosan solution containing dispersed Fe3O4 nanoparticles. The average particle size of prepared composite magnetic microsphere was about 10μm , due to the spherical, dispersive, magnetic-responsive and biodegradable characteristic, the composite magnetic chitosan microsphere can be used as functional material or carrier for targeted delivery of drugs.

关键词： Fe3O4 magnetic nanoparticle chemical co-precipitation emulsification crosslinking technique composite microsphere

作者: 赵原璧 邱祖民 刘钟薇

作者单位: 南昌大学 环境科学与工程学院,江西南昌,330029

会议类型: 国际会议

会议名称: 第六届中国国际纳米科技研讨会

会议地点: 成都

会议语种:英文

在线出版日期: 2007-11-19（万方平台首次上网日期，不代表论文的发表时间）