A DIFFUSION-BASED APPROACH FOR NANOBEAD DRAG FORCES
A central process of the Bead Array Counter (BARC) biosensor involves propelling a dilute solution of streptavidin-coated micron-scale beads through water. It is desirable to downsize these beads, leading to a basic engineering problem: What is the drag force acting on a nanoscale bead having an unknown hydrodynamic boundary condition? We use molecu-lar dynamics simulation to estimate the drag force acting on a hypothetical biosensor nanobead without assuming a no-slip condition or a user-supplied slip parameter.
Timothy W. Sirk Professor Eugene F. Brown
Mechanical Engineering Department Virginia Polytechnic Institute and State University Blacksburg, VA 24060
国际会议
海南三亚
英文
2007-01-10(万方平台首次上网日期,不代表论文的发表时间)