INFLUENCE OF MICROSTRUCTURE ON THE BINDER RATIO OF Β -TCP TISSUE SCAFFOLDS USING SELECTIVE LASER SINTERING
The growing interest in scaffold-guided tissue engineering (TE) to guide and support cell proliferation in the repair and replacement of bonedefects gave rise to the quest for a precise. Rapid prototyping (RP) has been identified as a promising technique capable of building complex objects with pre-designed macro-and microstructures. Calcium phosphate ceramics are biocompatible and may develop interactions with human living bone tissues. They are used clinically on the surface of orthopedic implants to improve primary fixation or in the form of porous blocks. The research focused on the macro and micro-structure of using the selective laser sintering (SLS) technique for creating porous tissue engineering scaffolds. The composite blends obtained by physical blending nano TCP and micro polymer powder binders. The SLS-fabricated test specimens were characterized using XRD and scanning electron microscopy. The total porous volume of the ceramics was over 70％ and the pore size from several μ m to 600 μ m. The results obtained ascertained that SLS-fabricated scaffolds have good potential for TE applications.
Bone tissue engineering RapidPrototyping Porous scaffold β -tricalcium phosphate
Liulan Lin Qingxi Hu Li Zhao Minglun Fang
Rapid Manufacturing Engineering Center, Shanghai University, Shanghai, China Shanghai Tissue Engineering Research & Development Center, Shanghai, China
国际会议
海南三亚
英文
2007-01-10（万方平台首次上网日期，不代表论文的发表时间）