Base catalysis via amine-functionalized mesoporous silicas with various structural phases
Chloropropyl functionalized mesoporous silicas with various structural phases such as hexagonal p6mm, cubic Ia3d, and cubic Im3m have been synthesized from the cocondensation of sodium metasilicate and 3-chloropropyltrimethoxysilane (CPTS) in a P123 or F127/HCl/H2O system. The mesostructural phase of the mesoporous silicas was closely related with the amount of CPTS in the initial synthesis gels when P123 was used as the structure directing agent. On the other hand, the amount of CPTS did not alter the mesostructure of the materials when F127 was used as the structure directing agent. The tetraalkyl quaternary ammonium hydroxide functionalized mesoporous silica catalysts were prepared from the obtained chloropropyl-functionalized mesoporous silicas. Over these catalysts we conducted Claisen-Schmidt condensation of benzaldehyde and 2’- hydroxyacetophenone and subsequent Michael addition to give a pharmaceutically important flavanone compound. The catalyst with Ia3d phase showed higher catalytic activity which was supposed due to the favorable diffusion and mass transfer of substrate molecules into the bicontinuous cubic interwoven pore structure than other cubic and hexagonal structures.
Sujandi Sang-Eon Park
Lab. Of Nano-Green Catalysis and Nano Center for Fine Chemicals Fusion Technology, Dep’t of Chemistry, Inha University, Incheon 402-751, Korea
国际会议
北京
英文
2007-08-12（万方平台首次上网日期，不代表论文的发表时间）