Preparation of Bovine Serum Albumin/poly (acrylic acid) Nanoparticles by Self-assembly
Natural macromolecule bovine serum albumin (BSA) and polyelectrolyte poly (acrylic acid) (PAA) were used to produce nanoparticles by a green and convenient method. The BSA/ PAA mixtures solutions were prepared by dropwise adding of the PAA solution into the pH adjusted BSA solution under agitation. The BSA chains are supposed to be partly trapped in the nanoparticles core after interaction with PAA as a result of the electrostatic attractions and H-bonding interaction between BSA and PAA, while the rest of the BSA chains might form the shell of the nanoparticles. The size and distribution of the nanoparticles are controlled by the medium of pH value. which might be good candidates for cosmetic and pharmaceutical applications.
Bovine Serum albumin PAA nanoparticles
WANG Yansong ZHANG Youwei WU Chengxun ZHAO Jiongxin
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620 P. R. China
国际会议
上海
英文
836-838
2007-10-15（万方平台首次上网日期，不代表论文的发表时间）