Detecting Human Optic Radiations Using Diffusion Probability Tractography with Combination of Cytoarchitectonic Probability Map
Investigating the relationship between human brain structure and function is one of the most important and exciting tasks in neuroscience. Nothing defines the function of a brain area more faithfully than the nature of its inputs and outputs. In this study, we detect the visual pathways using DW-MRI and explore the feasibility of using a cytoarchitectonic map to define the seed mask. Fourteen healthy male adult subjects participated in the study. DW-MRI datasets with higher angular resolution were acquired on a Siemens Sonata 1.ST MR scanner. In the calculations, the seed region or the lateral geniculate body was defined according to the 40％ cytoarchitectonic map, and diffusion probabilistic tractography was run from the seed mask for each subject to detect the fibres of the optic radius. We have obtained the optic fibre pathways for each subject and constructed the group mean connectivity map. The results demonstrated that the optic radiation seeding from LGB and entering the primary visual cortex is accordance with the anatomic knowledge. This suggests that it is feasible to use the cytoarchitectonic map to define the seed mask in tractography.
diffusion tensor retinotopic connectivity lateral geniculate body (LGB) primary visual cortex
Ruiwang Huang N. Jon Shah
Institute of Neurosciences and Biophysics-INB3 (Medicine), Research Centre Juelich, 52425 Juelich, Germany
国际会议
首届国际断层影像解剖学研讨会(The 1st International Symposium on Sectional and Inaging Anatomy)
青岛
英文
10-13
2007-12-15（万方平台首次上网日期，不代表论文的发表时间）