The Deep Cerebellar Nuclei: A Comparative. Study between Thin Transverse Sectional Anatomy and Magnetic Resonance Imaging
PURPOSE: The local-ization of the deep cerebellar nuclei is essential in the clinical research of cerebellum. Our research aimed to discriminate the locations of the nuclei on the thin transverse sections and supply anatomic reference for the functional imaging research of cerebellum and stereotactic operations of the correlative motor disorders. MATERIALS AND METHODS: After MRI examination to exclude organic lesions, one head specimen was selected from three cadavers, then embedded with gelatin and frozen under profound hypothermia. Subsequently, the specimen was sliced into 0.1mm transverse sections along AC-PC line with SKC500 computerized freezing milling machine. The sections were photographed and saved in the computer. Finally, the representative sections were observed meticulously, and equivalent in vivo MR images were selected for comparison with the corresponding sections to predict the location and configuration of the cerebellar nuclei. RESULTS: On the sections, the nuclei were four in number on either side, the dentate nucleus appeared as a convoluted band of gray matter on most sections. The fastigial nucleus was situated to the middle line at the anterior end of the superior vermis, and over the roof of Ⅳ ventricle. The emboliform nucleus lay immediately to the medial side of dentate nucleus, and partly covered its hilus. The globose nucleus was an elongated mass, directed anteroposteriorly, and placed medial to emboliform nucleus. CONCLUSION: The locations of the cerebellar nuclei could be discriminated clearly in our data, which could be seen as an anatomic reference for functional imaging research of cerebellum and clinical applications involving with the nuclei.
Lingzhong Fan Yuchun Tang Bo Sun Xiangtao Lin Zhenping Li Hengtao Qi Shuwei Liu
Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 25 Shandong Medical Imaging Research Institute, Jinan, 250012
国际会议
首届国际断层影像解剖学研讨会(The 1st International Symposium on Sectional and Inaging Anatomy)
青岛
英文
65-72
2007-12-15（万方平台首次上网日期，不代表论文的发表时间）