Separation of L-Ribose from L-Arabinose Using a Continuous Counter-Current Ligand-Exclusion Chromatography

摘要：

For the separation of L-ribose from L-arabinose, simulated moving bed (SMB), a form of a continuous counter-current chromatography, was employed. The jacketed glass column (2.5 cm I.D. × 19.7 cm bed-height) packed with Dowex 50WX4 (Ca 2+ form) was used at 50oC. Single-step frontal analysis was performed to estimate the adsorption isotherm parameters of L-ribose and L-arabinose. The experimental results showed that the adsorption behaviors of L-ribose and L-arabinose were competitive Langmuir isotherm model. With the estimated isotherm and kinetic parameters, the SMB process for the separation of L-arabinose and L-ribose was designed and simulated. SMB experiments were carried out to confirm the simulation results.

关键词： L-ribose L-arabinose SMB Ligand-exclusion chromatography continuous counter-current

作者: Yoon Mo Koo Jin-Il Kim Ju Weon Lee Jeoung Kun Kim

作者单位: Department of Biological Engineering, Inha University;ERC for Advanced Bioseparation Technology, Inh Department of Biological Engineering, Inha University ERC for Advanced Bioseparation Technology, Inha University, 253 Yonghyun-dong, Nam-gu, Incheon 402-7

会议类型: 国际会议

会议名称: The 5th International Conference on Separation Science and Technology(第五届国际分离科学与技术会议)

会议地点: 北京

会议语种:英文

在线出版日期: 2007-10-14（万方平台首次上网日期，不代表论文的发表时间）