Extraction of Residual Solvents in Cefpodoxime Proxetil
Extraction of residual solvents in oral drug-Cefpodoxime proxetil(CPD) was carried out by liquid and supercritical CO2. High pressure soxhlet equipment was used to use liquid CO2 as extracting solvent and in the supercritical extraction, CO2 was supplied continuously instead of recycle. The residual solvent contents were examined with extraction time. Pressure and temperature conditions controlled by heat input variation did not contribute to the degree of extraction. The results were analyzed by gas chromatography.
Supercritical CO2 liquid CO2 residual solvents extraction
Young Ho Shin Youn Woo Lee Nae Chul Shin Junho Chu
School of Chemical & Biological Engineering and Institute of Chemical Processes, Seoul National University, San 56-1, Sillim-dong, Gwanak-gu, 151-744, Seoul, Korea
国际会议
The 5th International Conference on Separation Science and Technology(第五届国际分离科学与技术会议)
北京
英文
2007-10-14（万方平台首次上网日期，不代表论文的发表时间）