Multivalent cellular surface recognition based on molecular motion of cyclodextrins in polyrotaxanes

摘要：

Multivalent protein recognition is important event to inform cellular signals. In order to recognize specific proteins on cellular surface using artificial multivalent ligands, optimum molecular design of polymeric architecture is needed. In this paper, role of polyrotaxanes in which a-cyclodextrins are threaded onto a poly(ethylene glycol) chain is summarized with some examples.

关键词： Multivalent interaction polyrotaxanes cellular recognition

作者: Tooru Ooya Nobuhiko Yui

作者单位: Department of Intelligent Systems Design Engineering, Toyama Prefectural University, Toyama 939-0398 School of Materials Science, Japan Advanced Institute of Science and Technology, Ishikawa 923-1292,

会议类型: 国际会议

会议名称: The 5th International Forum on Post-genome Technologies(5IFPT)(第五届国际后基因组生命科学技术学术论坛)

会议地点: 苏州

会议语种:英文

在线出版日期: 2007-09-10（万方平台首次上网日期，不代表论文的发表时间）