Investigation on the Sensitivities of Single and Combined Antitumor Drugs in Vitro by Real-Time Cell Electronic Sensing Technology
We creatively investigated and compared the chemosensitivity of 16 kinds of antitumor drugs either single or combined on A549 and PLC cells by a real-time cell electronic sensing (RT-CES) system. We got several sensitive drugs for A549 and PLC cells respectively, and summarized many kinds of effective clinical combination proposals. It was found that the average inhibition ratio on A549 cells was higher than PLC cells. It is concluded that the RT-CES system is a simple and rapid method for detecting chemosensitivity of anticancer drugs in vitro and it is conducive to give the reference guidance for clinical individualized treatment.
cell-based assay antitumor drug chemosensitivity drug combinatio
Xuan Liu Zaozao Chen Ying Luan Mengdie Qian Huihua Deng Zuhong Lu
Key Laboratory of Child Development and Learning Science of Ministry of Education, Southeast Univers Key Laboratory of Child Development and Learning Science of Ministry of Education, Southeast Univers
国际会议
The 5th International Forum on Post-genome Technologies(5IFPT)(第五届国际后基因组生命科学技术学术论坛)
苏州
英文
2007-09-10（万方平台首次上网日期，不代表论文的发表时间）