Study on DNA electrochemistry biosensor by self-assembling thiol DNA

摘要：

A simple DNA biosensor was fabricated by self-assembling thiol DNA on gold electrode for detecting complementary and non-complementary DNA probes, the self-assembling time, the blocking time and the ability of detecting were studied by anodic stripping voltammetry and gold-label-silver-stain. The results indicated that the optimal self-assembling time is 6 h, the optimal blocking time is 3 h with 6-Mercapto-1-hexanol as the blocking agent, and the DNA biosensor detects complementary or non-complementary DNA probes quickly and exactly.

关键词： biosensor gold-label-silver-stain self-assembly anodic stripping voltammetry

作者: Li-Jian Xu Jing-Jing Du Nong-Yue He Ya-Fei Guo Zhi-Yang Li Ting Wang

作者单位: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southe Huan Key Laboratory of Green Packaging and Application of Biological Nanotechnology, Hunan Universit State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southe

会议类型: 国际会议

会议名称: The 5th International Forum on Post-genome Technologies(5IFPT)(第五届国际后基因组生命科学技术学术论坛)

会议地点: 苏州

会议语种:英文

在线出版日期: 2007-09-10（万方平台首次上网日期，不代表论文的发表时间）