Effect of maternal nutrition in the third trimester on fetal growth
To investigate the relationship between the dietary intake of normal pregnant women in Nanjing, China during the third trimester and fetal growth and birth weight. Methods: Nanjing women, in their 32 week, that visited the Prenatal Clinic at Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, from January 2005 to April 2006 were enrolled for potential entry into this study. The exclusive cases were abnormal glucose challenge test, B type hepatic disease, cardiovascular, renal and/or other endocrine diseaseshistory. There were 799 women were included in this study. All participants were required to make a 24-hour dietary recall once prior to each of their scheduled visits during the 32nd, 34th, and 36th weeks of pregnancy respectively. At each of these three visits, their weights were recorded, and the dietary recall forms were collated by intake of various nutritional elements. Meanwhile they received ultrasound scan two times at about 28th weeks and 38th to measure fetal head circumference(HC), abdomen circumference(AC), femoral bone and humeral bone length(FL,HL) and biparietal diameter(BPD).Fetal birth weight was measured after delivery immediately. Result: Fetal birth weight tended to increase in pregnant women in relationship to fat intake. The proportion of energy derived from fat was related to fetal increased HC, AC and FL development in late pregnancy. HC increased 3.86mm(95％ CI:0.56mm to6.93mm) and AC increased 2.27mm(95％ CI:0.23mm to 4.45mm) as well as FL increase 1.35mm(0.26mm to 2.43mm) for each 1％ increase in the proportion of energy derived from fat. FL increase 2mm(95％ CI:0.15mm to 4.11mm) for each 100 mg increase with calcium intake ; BPD increased 0.53mm(95％ CI:0.02mm to 1.47mm), 1.51mm(95％ CI:0.12mm to 2.97mm), 1.79mm(95％ CI:0.26mm to 3.88mm) and 2.48mm (95％ CI:0.64mm to 5.03mm)for each 1mg increase in intake of Zn(P=0.05),VitE(P=0.016),VitB1(P=0.021),VitB2(P=0.033). Conclusion: Both the amount and density of fat intake in pregnant women was a significant factor in fetal birth weight, and increased fat intake during the third trimester can induce more macrosomia.
maternal nutrition third trimester pregnancy macrosomia
Yl Hu XP Ren ZQ Wang T Ru BY Xu XQ Ren
Department of Obstetrics & Gynecology, NanJing Drum Tower Hospital, the Affiliated Hospital of Nanji Medical college of Southeast University, Nanjing, China
国际会议
The 5th International Forum on Post-genome Technologies(5IFPT)(第五届国际后基因组生命科学技术学术论坛)
苏州
英文
2007-09-10（万方平台首次上网日期，不代表论文的发表时间）