Environmental and Genetic Risk Analysis for Gastric Cancer in a Chinese Population
A 1∶1 case-control study was accomplished in Nanjing, Jiangsu Province, China. A conditional-logistic regression model was used to determine environmental and genetic risk factors among 374 cases of gastric cancer patients and controls. The environmental risk factors of gastric cancer in the Nanjing area are family history of tumor, tobacco smoking, consumption of pickled food, engorgement after hunger, irregular dietary habits，and lack of fruit intake. The genetic risk factors are genetic polymorphisms of CYP2E1, NAT2M1, NAT2M2, XRCC1,and IL-1B. The results suggest that genetic polymorphisms and environmental risk factors play co-operating roles in the development of gastric cancer.
Gastric cancer Risk factors Genetic polymorphisms
Xiao-bing Shen Jiao Zhang Yufeng Yang Gang Fu Yuepu Pu
Department of Occupational and Environmental Health Science, School of Public Health, Southeast University
国际会议
The 5th International Forum on Post-genome Technologies(5IFPT)(第五届国际后基因组生命科学技术学术论坛)
苏州
英文
2007-09-10（万方平台首次上网日期，不代表论文的发表时间）