Edge Detection Based on Multi-resolution Analysis in Cryo-electron Micrograph Images

摘要：

Selecting hundreds of thousands of particles from low contrast and low SNR Cryo-electron micrograph (Cryo-EM)images is one of the major bottle-necks in advancing toward achieving atomic resolution reconstruction of biological macromolecules. To recognize true particles from impurities and other invalid particles, shape information plays a significant role.This paper provide a new method based on multi-resolution analysis to detect the main edges of objects in Cryo-EM image,which can be the pre-processing operations of next step ofparticle identification.

关键词： edge detection Cryo-electron micrograph multiresolution analysis wavelet decomposition particle-picking

作者: Xiaorong Wu Xiaoming Wu Tiejun Yang

作者单位: School of Computer Science and Engineering, South China University of Technology, Guangzhou P.R.Chin School of Biological Science and Engineering, South China University of Technology, Guangzhou P.R.Ch School of Computer Science and Engineering, South China University of Technology, Guangzhou P.R.Chin

会议类型: 国际会议

会议名称: The 1st International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2007)(首届IEEE生物信息与生物医学工程国际会议)

会议地点: 武汉

会议语种:英文

页码: 356-359

在线出版日期: 2007-07-06（万方平台首次上网日期，不代表论文的发表时间）