EECP induced instant shear stress variation-experiment and math modeling

摘要：

To study how the enhanced external counter pulsation (EECP) performance in uencesthe arterial hemodynamic factors, and then evaluate its anti-atherogenesis effect, a kind of long-term EECP animal experiment was designed in vivo. Some basic hemodynamics factors including bloodflow rate and blood pressure are obtained inside the carotids of the experimental animals togetherwith the cardiogram and carotids geometrical data.At the same time, a theoretical three-dimensional model of pulsatile blood ow through a vessel withan asymmetric stenosis was developed based on the experimental results. To study the blood velocityvector, arterial wall shear stress distribution numerically. By comparing the experimental and numer-ical hemodynamics factors of post-EECP and the pre-EECP state, the hemodynamics mechanism ofhow the EECP performance in uences the propagation and generation of the atherosclerotic lesionsis analyzed.

关键词： atherogenesis hemodynamic EECP WSS (wall shear stress) arterial stenosis

作者: J.H.Du C.L.Wu Z.S.Zheng G.Dai

作者单位: Department of Engineering, Guangdong Ocean University, Zhanjiang 524088, China Key Lab.On Assisted Circulation, Ministry of Health, Guangzhou 510089, China

会议类型: 国际会议

会议名称: The Fifth International Conference on Fluid Mechanics(第五届国际流体力学会议)

会议地点: 上海

会议语种:英文

在线出版日期: 2007-08-15（万方平台首次上网日期，不代表论文的发表时间）