A Computational Framework and Browser for Supporting Automatic Genome Annotation

摘要：

We present here a flexible computational framework to complete the large-scale computing tasks involved in automatic annotation of whole-genomes.The characteristics of this framework include a two-level job load system and NFS-based distributed store of replicated data. In addition, the storage structure of annotation results in a relational database system and a web interface for graphical interactive browsing and searching on the data are also described.The framework has been used to identify a core set of human protein coding genes that are consistently annotated and of high quality, which can be accessed by the browser provided at http://bioinfo. hust. edu. cn/en/database/ben.

作者: Feng Lu Ji Zhang Yanhong Zhou

作者单位: School of Compute Science and Technology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China

会议类型: 国际会议

会议名称: 第五届网格与协同计算国际会议(The Fifth International Conference on Grid and Cooperative Computing GCC 2006)

会议地点: 长沙

会议语种:英文

页码: 389-396

在线出版日期: 2006-10-21（万方平台首次上网日期，不代表论文的发表时间）