Serum β-carotene, lycopene and α-tocopherol levels of healthy people in northeast Thailand
Human serum contains many different antioxidants which may be important in the maintenance of antioxidant status. β-carotene and lycopene are carotenoids with potent antioxidant activity. Carotenoids intake probably protects against cancers and may affect the risk of several chronic conditions. α-tocopherol is well known for its function as antioxidant and in reduction of heart disease and cancer risk. We aimed to establish baseline values for serum β-carotene, lycopene and α-tocopherol concentrations in healthy northeast Thais. Fasting serum β-carotene, lycopene and α-tocopherol levels from 294 subjects aged 23-75 years old in northeast Thailand were determined by high performance liquid chromatography (HPLC). The mean serum β-carotene, lycopene and α-tocopherol levels were 0.53 ± 0.32 μ mol/L, 0.57±0.37 μmol/L, and 26.64 ± 14.85 μmol/L respectively. Serum β-carotene and lycopene levels in females (N =118) were significantly higher than the value for males (N =176),ie 0.60 ± 0.31 μmol/L versus 0.48 ± 0.32 μmol/L (p =0.002) for β-carotene and 0.74 ± 0.38 μ mol/L versus 0.46 ± 0.33 μmol/L (p＜0.001) for lycopene whereas α-tocopherol level in males (28.60 ± 14.34 μmol/L) was significantly higher than in females (23.72 ± 15.16 μmol/L) (p =0.006). β-carotene level was positively correlated with α-tocopherol (r=0.22, p＜0.001) and lycopene levels (r=0.63, p ＜0.001). The results from this study give the baseline data of serum β-carotene, lycopene and α-tocopherol levels in healthy northeast Thai population and also suggest future study on the relationship of dietary intake.
β-carotene lycopene α-tocopherol northeast Thais HPLC
Patcharee Boonsiri Jureerut Pooart Roongpet Tangrassameeprasert Pranithi Hongsprabhas
Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand Department of Clinical Chemistry, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
国际会议
国际营养科学联盟第八届临床营养学大会暨第五届亚太临床营养学会大会
杭州
英文
47-51
2006-10-01（万方平台首次上网日期，不代表论文的发表时间）