Antimicrobial effect of Chitooligosaccharides Produced by Chitosanase from Pseudomonas CUY8
The aim of this study was to investigate the antimicrobial effect of chitooligosaccharides prepared by chitosanase from Pseudomonas CUY8. Antimicrobial activities of different degrees of deacetylation (DD) and polymerization (DP) of chitooligosaccharides against various species of bacteria and fungi were measured. The antimicrobial effects of chitooligosaccharides compared with chitosan and chitosanase were evaluated. Inhibitory diameter of chitooligosaccharides at the concentration of 0.1％ with DP 4 was 19 ± 0.20mm, and inhibitory activity with DD 90％ was 79± 2.1％, which were higher than other DP and DD, respectively. The results showed that antimicrobial activities of chitooligosaccharides increased with increase of DD, but decreased with increase of DP. Chitooligosaccharides, chitosan and chitosanase all showed significantly stronger antimicrobial activities against bacteria than fungi (p＜0.001). Antimicrobial activities of chitooligosaccharides were significantly higher than that of chitosan (p＜0.05), but insignificantly lower than that of chitosanase (p＞0.05).
chitooligosaccharides antimicrobial effect chitosanase chitosan
Yan Wang Peigen Zhou Jianxing Yu Xiaorong Pan Pingping Wang Weiqing Lan Shendan Tao
Department of Food Science, Shanghai Fisheries University, Shanghai, China
国际会议
国际营养科学联盟第八届临床营养学大会暨第五届亚太临床营养学会大会
杭州
英文
174-177
2006-10-01（万方平台首次上网日期，不代表论文的发表时间）