The Study on the Treatment of Mice Inoculated S-180 with Electrochemotherapy
Electrochemotherapy (ECT) is a new efficient approach which treats tumor by electroporation and chemotherapeutic agents. Electroporation can deliver exogenous molecules such as drugs into cell by pulsed electric fields through a temporary increase in cell membrane permeability. It results in much higher uptake of the drugs and better effect of antitumoral treatment. We have performed the experiments on mice inoculated S-180 using gene pulser transfection apparatus LN-101 and needle electrodes combined with antitumor drugs. Inhibitory rates of ECT with antitumor drugs Cyclophosphamide (CTX) and Bleomycin(BLM) are 60.9％ and 70.4％ respectively, and are enhanced significantly in contrast to other methods in the experiments.
Electrochemotherapy electroporation tumor treatment needle electrode
Baoqiang Xu Yun Sun Junfa Zhao Zhengrong Tong Qiping Yuan Yuanyuan Gong Qian Sun Shixian Wang
School of Electronics Information and Communications Engineering, Tianjin University of Technology, School of Electronics Information and Communications Engineering, Tianjin University of Technology, Tianjin Renmin Hospital, Tianjin, 300121 Tianjin Institute of Medicine and Pharmacopeia, Tianjin, 300070
国际会议
北京
英文
496-499
2007-05-23（万方平台首次上网日期，不代表论文的发表时间）