A Correlation Analysis on Multiplex Three-Dimensional Brain Gene Expression Mapping of Parkinson Disease

摘要：

This paper is aimed to predict Parkinson disease (PD) genes from multiplex Three-Dimensional brain gene expression mapping. First, we select the available data from the original datasets and use log ratio as the object that we would analysis. Second, correlation coefficient calculated provides information on the correlation between genes based on gene expression levels. Later, classification and hierarchical cluster analysis can help us to find the relevant genes of Parkinson disease. The 27 genes selected by the statistical method are worthy of further experiments to assess the results of microarray.

关键词： PD correlation coefficient classification hierarchical cluster analysis

作者: Qiang Liu Haiyun Li

作者单位: Biomedical Engineering Institute, Capital Medical University, No. 10 Xi tou tiao, You an men Beijing, 100069 P.R. CHINA

会议类型: 国际会议

会议名称: 2007 IEEE/ICME International Conference on Complex Medical Engineering-CME2007(CME2007 第二届国际复合医学工程学术大会)

会议地点: 北京

会议语种:英文

页码: 1622-1625

在线出版日期: 2007-05-23（万方平台首次上网日期，不代表论文的发表时间）