Radical Scavenging Activity of Various Fractions of Cephalotaxus sinensis (Rehd et Wile) Li
Cephalotaxus sinensis (Rehd et Wile) Li, belongs to family Cephalotaxaceae, common in China, is an indigenous medicinal plant due to its antiascariasis, antiinflammation, anticough and antidyspepsia activity. The overindulgence of free radicals has been concerned in the development of chronic diseases and play an imperative role in the development of neurodegenerative disorders, such as Alzheimers and Parkinsons diseases. Various fractions of this plant were evaluated for their radical scavenging activity by the DPPH·and reducing power activity assays. Also, the Folin-Ciocalteu method was used to determine the total phenolic content. The results of both methods revealed that Cephalotaxus. sinensis possesses potent antioxidant activity. The polyphenolic content and antioxidant activities of the different fractions tested decreased in the order of EaF ＞ BtF ＞ CfF ＞ WtF ＞ PtF. The radical scavenging activity of the ethyl acetate fraction higher than BHT and slightly lower than Vit-C. A positive linear correlation between antioxidant activity and contents of polyphenol was established. This information shows that ethyl acetate fraction of C. sinensis can be used as antioxidant in medicinal preparations.
extraction fractionation polyphenols DPPH reducing power activity Cephalotaxus sinensis
Muhammad Khalid Saeed Yulin Deng Z. Parveen Rongji Dai W. Ahmad Yuhong Yu
School of Life Sciences and Technology, Beijing Institute of Technology,Beijing 100081, China
国际会议
北京
英文
1679-1682
2007-05-23（万方平台首次上网日期，不代表论文的发表时间）