Analyses of PAHs Metabolites Using A Peroxynitrite/Fe(Ⅲ) porphyrin Biomimetic System by HPLC

摘要：

The peroxynitrite/Fe(Ⅲ)porphyrin chemical system was established firstly to investigate the effects of peroxynitrite on the metabolism of polycyclic aromatic hydrocarbons(PAHs). By comparing the conversion ratio of benzoapyrene (BaP) in four model systems consisting of different iron porphyrins, we found that the peroxynitrite/T(p-Cl)PPFeCl system showed the highest catalytic efficiency, which conversion ratio of BaP reached 20.71％. We also analyzed the metabolites of BaP and pyrene (PN) produced from this system by HPLC and MS methods, and successfully identified the formation of nitrobenzoapyrene and nitropyrene which are the special metabolites induced by peroxynitrite.

作者: Yunjing Luo Rui Liu Yuanbin She Rugang Zhong

作者单位: College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100022,China College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100022, C

会议类型: 国际会议

会议名称: 2007 IEEE/ICME International Conference on Complex Medical Engineering-CME2007(CME2007 第二届国际复合医学工程学术大会)

会议地点: 北京

会议语种:英文

页码: 1766-1769

在线出版日期: 2007-05-23（万方平台首次上网日期，不代表论文的发表时间）