C-reactive Protein Immunoassay through Surface Plasmon Resonance Detection Based on A Microfluidic Platform

摘要：

C-reactive protein (CRP) is an acute phase reactant, and is an important biomarker whose concentration in serum can be used for monitoring inflammation and predicting atherosclerotic, cardiovascular events etc. In this study, surface plasma resonance(SPR) technology is adopted in combination with immunoassay for CRP concentration analysis and dynamic observation in limited time frame, thereby eliminating complicated labeling procedure and greatly reduce the complexity of the detection system. With corresponding fluid manipulation enabled by a microfluidic platform, this detection strategy holds the promise of being a point-of-care diagnostic approach.

关键词： C-reactive protein(CRP) Surface Plasma Resonance(SPR) microfluidic

作者: Xiansong Wang Yi Sun Fei Xie Juan Feng Xuemei Ma

作者单位: College of Life Science & Bioengineering, Beijing University of Technology, P.O. Box 825, 100＃ Pingleyuan, Chaoyang District, Beijing, 100022, P.R.. China

会议类型: 国际会议

会议名称: 2007 IEEE/ICME International Conference on Complex Medical Engineering-CME2007(CME2007 第二届国际复合医学工程学术大会)

会议地点: 北京

会议语种:英文

页码: 1780-1783

在线出版日期: 2007-05-23（万方平台首次上网日期，不代表论文的发表时间）