Investigation on photophysical properties of a substituted 3H-indole-modified β-cyclodextrin Ⅰ. Conformation in water and recognition mechanism as a chemosensor
A substituted 3H-indole-modified β-cyclodextrin (β-CD), mono-6-deoxy-(2-(p-amino) phenyl＞3,3-dimethyl-5-carboxyI-3H-indole)-β-CD (compound A) has been synthesized and characterized by elemental analysis, mass spectrum (MS) and H NMR. Induced circular dichroism (ICD), time-resolved fluorescence and computational analysis yield information on the molecular structure that compound A adopts rim-covering conformation in aqueous solution. It forms the 1:1 (guest:host) inclusion complex by addilion of native β-CD. Novel recognition behavior of compound A is investigated by means of ICD, time-resolved and steady-state fluorescence. In contrast to the behavior of most conventional CD-based chemosensors with self-inclusion conformation, the fluorescence intensity of this new kind chemosensor is increased upon addition of guest molecules. This new chemosensor exhibits high sensitivity to acyclic and adamantine molecules, but not to the bite acids.
Aihua Wu Qi Chen Ke Xia Tingjun Hou Xinghai Shen Hongcheng Gao Xiaojie Xu
Department of Applied Chemistry, College of Chemistry and Molecular Engineering, Peking University, Institute of Physical Chemistry, College of Chemistry and Molecular Engineering, Peking University,
国际会议
杭州
英文
1080-1086
2007-04-01（万方平台首次上网日期，不代表论文的发表时间）