Characterization of the Porous Scaffolds Prepared with Bombyx Mori Silk Fibroin Protein
A fusion protein was designed and produced by using the genetically engineering synthesis method, which was combined with a structural unit GAGAGS selected from the crystalline region of Bombyx mori silk fibroin and a functional unit, RGD sequence. Porous scaffolds were fabricated by adding different organic solvents or cross-linking agents into the fusion protein solution. A detailed investigation, including the swelling behavior, the SEM observation, the mechanical property and the cell adhesive ability, showed that the porous scaffolds could retain the original good compatibility to effectively accelerate cell infiltration and proliferation, suggesting that the fusion protein scaffold may be a potential candidate for tissue repairing with enhanced biostability and good biocompatibility.
Silk fibroin RGD Fusion protein Scaffold Cell adhesive ability
Yuan Li Juming Yao Liqiang Bai
Key Laboratory of Advanced Textile Materials and Manufacturing Technology,Ministry of Education, Hangzhou 310018,China
国际会议
杭州
英文
621-624
2006-08-22（万方平台首次上网日期，不代表论文的发表时间）