Multistage Evaluation of Measurement Error in a Reliability Study

摘要：

We introduce sequential testing procedures for the planning and analysis of reliability studies to assess an exposures measurement error. The designs allow repeated evaluation of reliability of the measurements and stop testing if early evidence shows the measurement error is within the level of tolerance. Methods are developed and critical values tabulated for a number of two-stage designs. The methods are exemplified using an example evaluating the reliability of biomarkers associated with oxidative stress.

关键词： Interim analysis Intraclass correlation Measurement error Power and sample size.

作者: Aiyi Liu Enrique F. Schisterman Chengqing Wu

作者单位: Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, NIH/DHHS, 6100 Executive Blvd., Rockville, MD 20852, U.S.A.

会议类型: 国际会议

会议名称: 2006 International Conference on Design of Experiments and Its Applications(2006实验设计及其应用国际会议)

会议地点: 天津

会议语种:英文

在线出版日期: 2006-07-09（万方平台首次上网日期，不代表论文的发表时间）