The fucoidan”s preparation, structure-bioactivity relationship from brown seaweeds
Fucoidan is a group of fucose-containing sulfated polysaccharides mainly derived from brown seaweeds,crude extracts of which are commercially available as nutritional supplements.Fucoidan has a backbone built of (1→3),(1→4),and (1→2)-linked α-L-fucose residues and also include sulfated with fucose or fuco-oligosaccharide branching,or other monosaccharide substitutions.Recent studies have demonstrated a variety of beneficial biological functions of fucoidan,including anticoagulant,antitumor,antithrombosis,antivirus,antioxidation as well as immunbomodulation.The content of fucoidan in brown seaweeds is not high,but its prominent physiological activities are attracting attentions from many industries all over the world.The versatile bioactivities vary depending on the source of seaweed,the structural and compositional properties,the sulfate content and substitution position,etc.The structural integrity of fucoidan molecular essentially due to the extraction methods is different,which are crucial for obtaining and elucidating structure-bioactivities relationship.This article discusses the fucoidan”s preparation,structure-bioactivity relationship from brown seaweeds.
Fucoidan Preparation Composition Structure Bioactivity
Peili Shen Chunxia Wang Zongmei Yin Guiyan Qu Yimin Qin
Qingdao Bright Moon Seaweed Co., Ltd., State Key Laboratory of Bioactive Seaweed Substances, Qingdao 266400, China
国内会议
青岛
英文
126-143
2017-09-20（万方平台首次上网日期，不代表论文的发表时间）